I 10 $east, I 75 $south
499.4 mi7 hours 41 mins
| Head southeast on Front Beach Road (FL 30) | 0.3 mi | |
| Turn left onto Alf Coleman Road | 0.9 mi | |
| Turn right onto Panama City Beach Parkway (US 98) | 5.8 mi | |
| Turn left onto West 23rd Street (FL 368) | 5.4 mi | |
| Turn left onto US 231 | 22.6 mi | |
| Turn right onto FL 20 | 28.4 mi | |
| Turn left onto FL 12 | 18.1 mi | |
| Turn right onto Selman Street (FL 12) | 0.6 mi | |
| Continue onto Greensboro Highway (FL 12) | 2.2 mi | |
| Take the ramp on the right | 0.5 mi | |
| Merge left onto I 10 E | 121.3 mi | |
| Take the ramp towards I-75 South: Tampa | 0.3 mi | |
| Merge left onto I 75 S | 107.5 mi | |
| Keep right towards I 75 South: Tampa | 53.5 mi | |
| Keep left towards South I 75: Naples | 16.2 mi | |
| Continue onto I 75 S | 58.3 mi | |
| Keep left onto I 75 S | 42.2 mi | |
| Take the ramp towards Tuckers Grade | 0.3 mi | |
| Keep left at the fork | 300 feet | |
| Turn right onto Tuckers Grade (CR 762) | 1.0 mi | |
| Turn left onto Tamiami Trail (US 41) | 11.4 mi | |
| Continue onto North Cleveland Avenue (US 41) | 2.1 mi | |
| Turn left onto Pine Island Road (FL 78) | 0.3 mi | |
| Make a U-turn and continue on Pine Island Road (FL 78) | 1,000 feet | |
| You have arrived at your destination |
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Panama City Beach, Florida - North Fort Myers, Florida