I 75 $south, I 75 $south; US 23 $south
298.9 mi5 hours 13 mins
| Head west on East Main Street | 300 feet | |
| Turn right onto South M 129 (M 129) | 2.0 mi | |
| Turn left onto West M 48 (M 48) | 10.0 mi | |
| Turn right onto South Centerline Road | 3.0 mi | |
| Turn right onto West M 48 Business Spur (M 48) | 0.4 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 75 S | 224.4 mi | |
| Take exit 149A towards M 46 East: Sandusky | 0.3 mi | |
| Go straight onto East Holland Avenue (M 46) | 9.8 mi | |
| Continue onto Sanilac Road (M 46) | 25.3 mi | |
| Continue onto State Street (M 46) | 1.0 mi | |
| Continue onto Sanilac Road (M 46) | 12.4 mi | |
| Turn left onto Ubly Road (M 19) | 10.0 mi | |
| You have arrived at your destination |
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Pickford, Michigan - Argyle, Michigan