US 23 $south, Ohio Turnpike
456.6 mi7 hours 18 mins
| Head west on Michigan Avenue | 0.5 mi | |
| Continue onto Pigeon Road (M 142) | 4.9 mi | |
| Turn left onto M 25 | 14.8 mi | |
| Turn right onto Bay Street (M 25) | 0.5 mi | |
| Continue onto West Bay City Forestville Road (M 25) | 12.7 mi | |
| Continue onto East Center Road (M 25) | 7.2 mi | |
| Continue onto Center Avenue (M 25) | 2.2 mi | |
| Turn left onto North Madison Avenue (M 25) | 700 feet | |
| Turn right onto 7th Street (M 25 W) | 0.3 mi | |
| Continue onto Veterans Memorial Bridge (I 75 Business) | 0.5 mi | |
| Continue onto East Jenny Street (I 75 Business) | 2.4 mi | |
| Continue onto US 10 W | 600 feet | |
| Take exit 140A towards I 75 South: Saginaw | 0.2 mi | |
| Merge left onto I 75 S | 47.7 mi | |
| Take the ramp towards US 23: Ann Arbor | 600 feet | |
| Continue towards US 23: Ann Arbor | 45.3 mi | |
| Keep left towards US 23 South: Plymouth | 0.5 mi | |
| Continue onto US 23 S | 1.9 mi | |
| Keep right towards US 23 South: Ann Arbor | 0.6 mi | |
| Continue onto US 23 S | 52.0 mi | |
| Take exit 6 towards Dussel Drive | 0.3 mi | |
| Turn left onto Salisbury Road (CR 91) | 900 feet | |
| Continue onto West Dussel Drive (CR 91) | 1.4 mi | |
| Turn left onto Reynolds Road (US 20) | 500 feet | |
| Take the ramp on the right | 0.5 mi | |
| Continue straight | 700 feet | |
| Keep right at the fork | 0.3 mi | |
| Merge left onto Ohio Turnpike (I 80 E) | 81.8 mi | |
| Keep left onto Ohio Turnpike (I 80 E) | 9.2 mi | |
| Keep right onto I 480 E | 26.3 mi | |
| Keep right onto Outerbelt South Freeway (I 480 E) | 2.5 mi | |
| Merge left onto Outerbelt East Freeway (I 271 S) | 3.0 mi | |
| Keep right towards I 480: Youngstown | 10.6 mi | |
| Take the ramp towards Youngstown | 0.5 mi | |
| Keep right towards Youngstown | 1,000 feet | |
| Merge left onto Ohio Turnpike (I 80 E) | 53.8 mi | |
| Continue onto Pennsylvania Turnpike (I 76 E) | 1.2 mi | |
| Keep left towards E-ZPass Express | 29.6 mi | |
| Keep right onto Pennsylvania Turnpike (I 76 E) | 36.5 mi | |
| Take the ramp towards US 30: Irwin | 0.4 mi | |
| Keep right towards US 30 East: Greensburg | 900 feet | |
| Merge left onto Lincoln Highway (US 30) | 800 feet | |
| Turn right onto Arona Road | 3.3 mi | |
| You have arrived at your destination |
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Pigeon, Michigan - Arona, Pennsylvania