I 65 $south, I 75 $south
1,155.8 mi18 hours 10 mins
| Head north on CTH W | 2.5 mi | |
| Turn left onto State Highway 64 (WI 64 W) | 0.3 mi | |
| Turn left | 0.3 mi | |
| Merge left onto US 51 | 19.6 mi | |
| Keep left towards I 39 South: Stevens Point | 98.8 mi | |
| Continue onto I 39 S | 4.3 mi | |
| Take the ramp onto I 39 S | 700 feet | |
| Keep left towards I 39 South: Madison | 116.9 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90) | 40.5 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90 E) | 1.0 mi | |
| Merge right onto Kennedy Expressway (I 90) | 5.6 mi | |
| Keep right onto Kennedy Expressway (I 90) | 8.3 mi | |
| Continue onto Dan Ryan Expressway (I 90) | 2.4 mi | |
| Keep left towards I 90 Express | 3.8 mi | |
| Take the ramp towards I 90 East: Chicago Skyway | 0.4 mi | |
| Merge right onto Dan Ryan Expressway (I 90) | 0.5 mi | |
| Keep left towards I 90 East: Chicago Skyway | 10.6 mi | |
| Keep left onto Indiana Toll Road (I 90) | 11.3 mi | |
| Take the ramp towards IN 53 | 0.3 mi | |
| Turn right onto Broadway (SR 53) | 0.2 mi | |
| Turn left onto East 5th Avenue (US 12) | 1.6 mi | |
| Turn right onto I 65 S | 132.7 mi | |
| Keep left onto I 65 S | 130.0 mi | |
| Take the ramp towards I 64: Lexington | 100 feet | |
| Keep left towards I 64 East: Lexington | 0.8 mi | |
| Merge left onto I 64 E | 175.4 mi | |
| Continue onto I 75 S | 64.6 mi | |
| Continue onto I 275 S | 0.3 mi | |
| Take the ramp towards I 640 East: Asheville | 0.2 mi | |
| Merge left onto I 640 E | 6.7 mi | |
| Keep left towards I 40 East: Asheville | 28.5 mi | |
| Keep right towards I 40 East: Asheville | 76.3 mi | |
| Take the ramp towards I 26 East: Hendersonville | 13.3 mi | |
| Continue onto I 26 E | 134.0 mi | |
| Take the ramp towards I 20 East: Florence | 0.3 mi | |
| Merge left onto I 20 | 55.5 mi | |
| Take the ramp towards SC 341: Bishopville | 0.3 mi | |
| Turn right onto Wisacky Highway (SC 341) | 2.8 mi | |
| Continue onto Elliott Highway (SC 527) | 4.6 mi | |
| You have arrived at your destination |
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Pine River, Wisconsin - Elliott, South Carolina