I 75 $south, I 77 $south
656.2 mi10 hours 48 mins
| Head west on Coolidge Highway | 0.5 mi | |
| Continue onto South Schaefer Highway | 0.8 mi | |
| Take the ramp on the left towards I 75 South | 0.4 mi | |
| Merge left onto Fisher Freeway (I 75 S) | 7.7 mi | |
| Continue onto Detroit-Toledo Expressway (I 75 S) | 53.8 mi | |
| Keep left onto I 75 S | 35.6 mi | |
| Take exit 156 towards US 68 | 2.5 mi | |
| Continue onto US 68 | 15.1 mi | |
| Continue onto US 23 | 7.2 mi | |
| Keep left onto US 23 | 56.2 mi | |
| Turn left onto East Powell Road (SR 750) | 0.7 mi | |
| Continue onto Polaris Parkway (SR 750) | 2.2 mi | |
| Take the ramp on the right | 0.5 mi | |
| Merge left onto I 71 S | 12.8 mi | |
| Take the ramp on the left towards I 70 East: Wheeling | 0.5 mi | |
| Merge right onto East Freeway (I 70) | 3.3 mi | |
| Take exit 105A towards US 33 East: Lancaster | 0.3 mi | |
| Merge left onto Southeast Expressway (US 33 E) | 9.1 mi | |
| Continue onto Columbus-Lancaster Road Northwest (US 33 E) | 7.6 mi | |
| Continue onto Lancaster Bypass (US 33 E) | 13.8 mi | |
| Continue onto Logan-Lancaster Road (US 33 E) | 3.5 mi | |
| Continue onto Logan-Lancaster Road Southeast (US 33 E) | 2.6 mi | |
| Continue onto Old Logan Road (US 33 E) | 31.6 mi | |
| Keep right towards US 33 East: Pomeroy | 0.2 mi | |
| Merge left onto James A. Rhodes Appalachian Highway (US 33 E) | 1.9 mi | |
| Keep right onto US 33 E | 19.0 mi | |
| Continue onto SR 833 | 1,000 feet | |
| Make a U-turn and continue on SR 124 | 1,000 feet | |
| Take the ramp onto SR 124 | 0.2 mi | |
| Turn right onto US 33 E | 18.6 mi | |
| Turn left onto US 33 | 2.7 mi | |
| Take the ramp onto US 33 E | 800 feet | |
| Merge left onto I 77 S | 145.2 mi | |
| Continue onto I 77 S | 26.5 mi | |
| Keep left towards I 77 South: Roanoke | 8.7 mi | |
| Take the ramp towards I 77 South: Charlotte NC | 89.1 mi | |
| Take the ramp towards Downtown Statesville | 0.2 mi | |
| Turn left onto Salisbury Road | 0.7 mi | |
| Turn left onto Salisbury Highway (US 70) | 12.8 mi | |
| Turn right onto NC 801 | 1.8 mi | |
| Turn left onto Sherrills Ford Road (1526) | 7.5 mi | |
| Turn left onto Mooresville Road (NC 150) | 1.5 mi | |
| Turn right onto Jake Alexander Boulevard West (US 70) | 3.6 mi | |
| Turn right onto East Innes Street (US 52) | 0.4 mi | |
| Continue onto North Salisbury Avenue (US 52) | 0.7 mi | |
| Continue onto North Salisbury Gq Avenue (US 52) | 3.9 mi | |
| Turn left onto Sides Road | 3.6 mi | |
| Turn left onto US 52 | 38.4 mi | |
| You have arrived at your destination |
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River Rouge, Michigan - Ansonville, North Carolina