I 65 $south, I 74 $east
374.8 mi6 hours 18 mins
| Head southeast on Walnut Street (US 20 Business) | 500 feet | |
| Continue onto 1st Avenue (US 20 Business) | 0.4 mi | |
| Turn right onto Charles Street | 0.5 mi | |
| Turn right onto 11th Street | 3.1 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto US 20 E | 5.8 mi | |
| Continue onto I 39 N | 0.6 mi | |
| Keep right towards I 90 East: Chicago | 0.4 mi | |
| Merge left onto Jane Addams Memorial Tollway (I 90) | 19.8 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90) | 40.5 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90 E) | 1.0 mi | |
| Merge right onto Kennedy Expressway (I 90) | 5.6 mi | |
| Keep right onto Kennedy Expressway (I 90) | 8.3 mi | |
| Continue onto Dan Ryan Expressway (I 90) | 2.4 mi | |
| Keep left towards I 90 Express | 3.8 mi | |
| Take the ramp towards I 90 East: Chicago Skyway | 0.4 mi | |
| Merge right onto Dan Ryan Expressway (I 90) | 0.5 mi | |
| Keep left towards I 90 East: Chicago Skyway | 10.6 mi | |
| Keep left onto Indiana Toll Road (I 90) | 11.3 mi | |
| Take the ramp towards IN 53 | 0.3 mi | |
| Turn right onto Broadway (SR 53) | 0.2 mi | |
| Turn left onto East 5th Avenue (US 12) | 1.6 mi | |
| Turn right onto I 65 S | 132.7 mi | |
| Keep left onto I 65 S | 16.8 mi | |
| Take exit 111 towards Michigan Street | 0.5 mi | |
| Keep left at the fork | 1.0 mi | |
| Keep right at the fork | 0.2 mi | |
| Turn left onto Fletcher Avenue | 800 feet | |
| Turn left onto Calvary Street | 400 feet | |
| Make a slight right onto English Avenue | 1.3 mi | |
| Go straight onto Southeastern Avenue | 3.6 mi | |
| Continue onto [Southeastern Avenue Connector] | 1.0 mi | |
| Continue onto I 74 E | 84.2 mi | |
| Merge right onto Cincinnati By-Pass (I 74 E) | 2.7 mi | |
| Keep right towards I 75 East: Cincinnati | 9.6 mi | |
| Continue onto I 74 E | 0.4 mi | |
| Keep right towards I 75 South: Lexington | 0.5 mi | |
| Merge left onto Mill Creek Expressway (I 75 S) | 0.3 mi | |
| Take exit 3 towards US 27 South: Hopple Street | 0.3 mi | |
| Turn left to stay on Hopple Street (US 27 S) | 200 feet | |
| Continue onto Hopple Street Viaduct (US 52 S) | 900 feet | |
| Continue onto Martin Luther King Drive West | 0.8 mi | |
| Make a slight right | 100 feet | |
| Turn right onto Clifton Avenue | 0.5 mi | |
| Turn left onto West McMillan Avenue | 0.3 mi | |
| Turn right onto Ohio Avenue | 100 feet | |
| You have arrived at your destination, on the left |
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Rockford, Illinois - Cincinnati, Ohio