I 70, I 80
1,362.3 mi20 hours 59 mins
| Head north on North Main Street (MO B) | 800 feet | |
| Turn right onto North Main Street (MO B) | 15.1 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 44 E | 194.8 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep left towards I 55 North: Chicago | 0.6 mi | |
| Merge right onto I 55 N | 15.5 mi | |
| Keep right towards I 70 East: Indianapolis | 223.7 mi | |
| Keep right towards 10 Street | 120.2 mi | |
| Keep left onto I 70 | 49.1 mi | |
| Keep left towards I 670 East: Airport | 4.3 mi | |
| Keep right towards I 71: Cincinnati | 0.2 mi | |
| Take the ramp towards I 71 North: Cleveland | 0.4 mi | |
| Keep left towards I 71 North: Cleveland | 0.3 mi | |
| Merge left onto North Freeway (I 71 N) | 99.5 mi | |
| Take exit 209A-B towards I 76: Lodi | 0.2 mi | |
| Keep right towards I 76: Akron | 0.9 mi | |
| Merge left onto I 76 E | 17.1 mi | |
| Keep right onto Kenmore Expressway (I 76 E) | 3.1 mi | |
| Keep left onto I 76 E | 39.1 mi | |
| Continue onto I 80 | 4.0 mi | |
| Keep left onto I 80 | 272.4 mi | |
| Take exit 260B on the left towards I 81 North: Wilkes-Barre | 0.7 mi | |
| Merge left onto I 81 N | 34.7 mi | |
| Take the ramp towards I-84 east | 0.4 mi | |
| Keep left at the fork | 0.3 mi | |
| Keep right towards I 84 East: Mt Pocono | 0.4 mi | |
| Continue onto I 84 E | 3.4 mi | |
| Take the ramp on the left towards I 84 East: Milford | 129.0 mi | |
| Keep right towards Waterbury | 0.8 mi | |
| Keep left onto Yankee Expressway (I 84 E) | 41.7 mi | |
| Keep right onto Yankee Expressway (I 84 E) | 12.7 mi | |
| Continue onto Bulkeley Bridge (I 84 E) | 0.2 mi | |
| Continue onto Grand Army of the Republic Highway (I 84 E) | 1.3 mi | |
| Keep left onto Grand Army of the Republic Highway (I 84 E) | 0.8 mi | |
| Merge left onto Wilbur Cross Highway (I 84 E) | 40.7 mi | |
| Keep right towards I 90 East: New Hampshire | 0.4 mi | |
| Merge left onto Massachusetts Turnpike (I 90 E) | 11.2 mi | |
| Take exit 10 towards I 395: Auburn | 0.3 mi | |
| Keep left at the fork | 0.7 mi | |
| Continue onto I 290 E | 14.8 mi | |
| Take exit 24 towards Northboro | 1,000 feet | |
| Keep left at the fork | 100 feet | |
| Turn left onto Church Street | 0.4 mi | |
| Continue onto Central Street | 2.5 mi | |
| Make a sharp right onto Linden Street | 0.4 mi | |
| You have arrived at your destination, on the left |
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Rogersville, Missouri - Massachusetts