How to get from Saint Paul, Minnesota to St Louis, Missouri

Discover, print or download the driving directions for the best route to go from Saint Paul, Minnesota to St Louis, Missouri.

Enlarge the route map Saint Paul, Minnesota - St Louis, Missouri

Driving directions from Saint Paul, Minnesota to St Louis, Missouri

Avenue of the Saints, Avenue of the Saints

528.8 mi8 hours 52 mins

Head northwest on Wabasha Street North 200 feet
Turn right onto East 4th Street 400 feet
Turn right onto Cedar Street 400 feet
Turn left onto Kellogg Boulevard 700 feet
Turn right onto Robert Street North 1.1 mi
Turn left onto Cesar Chavez Street 0.6 mi
Take the ramp on the right 0.3 mi
Merge left onto Lafayette Freeway (US 52 S) 11.4 mi
Take the ramp onto Clayton Avenue (US 52 S) 3.1 mi
Continue onto Coates Boulevard (US 52 S) 7.0 mi
Continue onto Emery Avenue (US 52 S) 1.8 mi
Continue onto Rochester Boulevard (US 52 S) 11.4 mi
Continue onto US 52 42.2 mi
Take exit 51 towards US 63 South: Broadway Avenue 0.2 mi
Keep right onto US 63 0.2 mi
Merge left onto South Broadway Avenue (US 63 S) 7.1 mi
Continue onto North Main Street (US 63) 2.1 mi
Continue onto United States Highway 63 (US 63) 9.2 mi
Turn left onto US 63 5.0 mi
Make a slight left onto West Grant Street (US 63) 700 feet
Turn right onto North Section Avenue (US 63) 35.1 mi
Continue onto McCloud Ave (US 63) 41.3 mi
Continue onto Logan Avenue (US 63 S) 7.9 mi
Continue onto East Mullan Avenue 2.3 mi
Keep left at the fork 0.2 mi
Go straight onto Washington Street 2.9 mi
Take the ramp towards I-380 south: Cedar Rapids 0.2 mi
Keep left towards I-380 south: Cedar Rapids 6.3 mi
Take the ramp towards I 380 South: Cedar Rapids 49.2 mi
Continue onto I 380 S 156.6 mi
Keep left towards US 61 South: Hannibal 6.7 mi
Continue onto McMasters Avenue (US 61 S) 1.1 mi
Continue onto Avenue of the Saints (US 61) 0.7 mi
Continue onto McMasters Avenue (US 61 S) 1.6 mi
Continue onto Avenue of the Saints (US 61 S) 112.8 mi
Take exit 39A towards 14th Street 0.2 mi
Turn left onto South 14th Street 0.3 mi
Turn right onto Market Street 500 feet
You have arrived at your destination

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Saint Paul, Minnesota - St Louis, Missouri

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