I 10, US 385 $north
439.4 mi7 hours 22 mins
| Head south on South Guadalupe Street (Loop 82) | 0.7 mi | |
| Turn right onto South I-35 Frontage | 900 feet | |
| Continue onto South Interstate 35 Frontage Road | 0.4 mi | |
| Make a slight left | 0.2 mi | |
| Merge left onto I 35 S | 31.0 mi | |
| Take the ramp towards Loop 1604 South: Anderson Loop | 0.7 mi | |
| Keep left towards Loop 1604 West | 600 feet | |
| Merge left onto Anderson Loop (Loop 1604 W) | 16.8 mi | |
| Take the ramp towards I 10 East: San Antonio | 600 feet | |
| Keep right towards I 10 West: El Paso | 0.4 mi | |
| Merge left onto Interstate 10 West (I 10) | 248.6 mi | |
| Take the ramp towards US 190: Iraan | 0.2 mi | |
| Continue onto Northeast 10 Frontage Road | 700 feet | |
| Turn right onto US 190 | 4.0 mi | |
| Turn left onto Farm to Market Road 305 (FM 305) | 18.2 mi | |
| Continue onto South Burleson Avenue (FM 305) | 19.6 mi | |
| Continue onto US 385 | 97.7 mi | |
| Turn left onto West Avenue A (US 180) | 900 feet | |
| Turn right onto Northwest 3rd | 500 feet | |
| Turn left | 100 feet | |
| You have arrived at your destination, on the right |
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San Marcos, TX - Seminole, TX