US 160 $east, I 25 $north
252.8 mi4 hours 9 mins
| Head north on Main Street (CO 136) | 0.8 mi | |
| Continue onto Ash Street (CO 136) | 1,000 feet | |
| Continue onto State Highway 136 (CO 136) | 2.9 mi | |
| Turn right onto United States Highway 285 (US 285) | 14.4 mi | |
| Continue onto West Avenue (US 285) | 0.2 mi | |
| Turn right onto 6th Street (US 160 E) | 0.6 mi | |
| Turn left onto Denver Avenue (US 160 E) | 0.2 mi | |
| Continue onto Broadway Avenue (US 160 E) | 0.3 mi | |
| Continue onto Santa Fe Avenue (US 160 E) | 20.6 mi | |
| Continue onto US Highway 160 (US 160 E) | 3.2 mi | |
| Continue onto 4th Street (US 160 E) | 47.6 mi | |
| Turn left onto Main Street (I 25 Business) | 0.4 mi | |
| Continue straight to stay on Main Street (I 25 Business) | 200 feet | |
| Continue slightly right onto Walsen Avenue (I 25 Business) | 2.3 mi | |
| Take the ramp towards I 25 North: Pueblo | 0.3 mi | |
| Merge left onto I 25 N | 46.5 mi | |
| Take the ramp towards 13th Street | 0.4 mi | |
| Merge left onto I 25 N | 0.6 mi | |
| Continue onto I 25 N | 109.8 mi | |
| Take exit 210A towards US 40 | 0.4 mi | |
| Keep right at the fork | 200 feet | |
| Merge left onto West Colfax Avenue (I 70 Bus) | 1.1 mi | |
| You have arrived at your destination |
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Sanford, Colorado - Denver, Colorado