How to get from Sioux Falls, SD, USA to St. Joseph, MO, USA

Discover, print or download the driving directions for the best route to go from Sioux Falls, SD, USA to St. Joseph, MO, USA.

Enlarge the route map Sioux Falls, SD, USA - St. Joseph, MO, USA

Driving directions from Sioux Falls, SD, USA to St. Joseph, MO, USA

I 29 $south, I 29 $south; US 275 $south

311.8 mi4 hours 32 mins

Head north 200 feet
Turn left onto West 14th Street 600 feet
Turn left onto South Minnesota Avenue (I 229 Business) 2.1 mi
Take the ramp on the right onto I 229 Business 0.2 mi
Merge left onto I 229 S 4.2 mi
Merge left onto I 29 S 177.8 mi
Keep right towards I 29 South: Kansas City 124.7 mi
Take the ramp towards MO 6: Clarksdale 0.3 mi
Turn right onto Frederick Avenue (MO 6) 0.5 mi
Turn left onto North Belt Highway (US 169) 1.0 mi
Turn right onto Messanie Street 0.6 mi
Turn right onto South 32nd Street 0.2 mi
Turn right 300 feet
You have arrived at your destination

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Sioux Falls, SD, USA - St. Joseph, MO, USA

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