How to get from St. Louis, Missouri to De Soto, Missouri

Discover, print or download the driving directions for the best route to go from St. Louis, Missouri to De Soto, Missouri.

Enlarge the route map St. Louis, Missouri - De Soto, Missouri

Driving directions from St. Louis, Missouri to De Soto, Missouri

I 55 $south, US 67

48.1 mi50 mins

Head east on Doctor Martin Luther King Drive (MO D) 0.3 mi
Turn right onto North Tucker Boulevard 1.8 mi
Go straight onto Gravois Avenue 0.3 mi
Take the ramp on the left 800 feet
Merge left onto I 55 S 32.7 mi
Take the ramp towards US 67 South: Farmington 0.5 mi
Merge left onto US 67 5.7 mi
Take the ramp 0.3 mi
Turn right onto MO 110 4.7 mi
Turn left onto North Main Street 1.7 mi
Turn left onto West Miller Street (MO N) 0 feet
You have arrived at your destination

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St. Louis, Missouri - De Soto, Missouri

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