How to get from St. Petersburg, FL, USA to Key West, FL, USA

Discover, print or download the driving directions for the best route to go from St. Petersburg, FL, USA to Key West, FL, USA.

Enlarge the route map St. Petersburg, FL, USA - Key West, FL, USA

Driving directions from St. Petersburg, FL, USA to Key West, FL, USA

I 75 $south, Overseas Highway

406.8 mi6 hours 53 mins

Head southwest on 8th Avenue 0.6 mi
Turn right onto 1st Street Southeast 800 feet
Turn left onto 6th Avenue South 0.3 mi
Turn right onto 4th Street South 500 feet
Take the ramp on the left 100 feet
Merge right onto I 175 W 1.0 mi
Keep left at the fork 0.5 mi
Merge left onto I 275 S 19.9 mi
Keep left towards I 75 South: Naples 1.0 mi
Merge left onto I 75 S 28.1 mi
Keep left onto I 75 S 175.8 mi
Take the ramp towards US 27: Miami 0.2 mi
Keep right towards US 27 South: Miami 0.5 mi
Merge left onto US 27 17.8 mi
Take the ramp on the left towards Florida's Turnpike Toll South 0.3 mi
Merge left onto Homestead Extension of Florida's Turnpike 35.4 mi
Merge left onto Dixie Highway (US 1) 19.3 mi
Continue onto Overseas Highway (US 1) 104.0 mi
Keep left onto Overseas Highway (FL A1A) 700 feet
Turn left onto South Roosevelt Boulevard (FL A1A) 0.3 mi
Turn right onto Flagler Avenue (CR 5A) 1.2 mi
Turn right onto 11th Street 300 feet
Turn left onto Staples Avenue 200 feet
You have arrived at your destination

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St. Petersburg, FL, USA - Key West, FL, USA

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