New York State Thruway, Highway 17
1,355.9 mi22 hours 33 mins
| Head southwest on Concord Road | 0.6 mi | |
| Keep right onto Union Avenue | 1.0 mi | |
| Turn right onto Boston Post Road (US 20) | 700 feet | |
| Turn left onto Nobscot Road | 1.2 mi | |
| Continue onto Edgell Road | 2.3 mi | |
| Keep right onto Edgell Road | 0.9 mi | |
| Make a slight right onto Vernon Street | 0.2 mi | |
| Turn right onto Pleasant Street (MA 30) | 500 feet | |
| Take the ramp on the left | 600 feet | |
| Merge left onto Worcester Road (MA 9) | 1.9 mi | |
| Take the ramp towards I 90 West: Masspike | 0.2 mi | |
| Continue towards I 90 West: Masspike | 0.5 mi | |
| Keep left towards I 90 West: Worcester | 0.6 mi | |
| Merge left onto Massachusetts Turnpike (I 90 W) | 111.0 mi | |
| Continue onto New York State Thruway Berkshire Connector (I 90 W) | 6.4 mi | |
| Merge right onto New York State Thruway Berkshire Connector (I 90 W) | 17.7 mi | |
| Keep right towards I 87 North: Albany | 0.5 mi | |
| Merge left onto New York State Thruway (I 87 N) | 285.4 mi | |
| Take exit 50 towards I 290: Niagara Falls | 0.4 mi | |
| Continue slightly right onto Youngmann Expressway (I 290 W) | 9.5 mi | |
| Keep right towards I 190 North: Niagara Falls | 0.3 mi | |
| Merge left onto Niagara Thruway (I 190 N) | 6.8 mi | |
| Continue onto North Grand Island Bridge (I 190 N) | 0.8 mi | |
| Continue onto Niagara Thruway (I 190 N) | 7.2 mi | |
| Continue onto Queenston–Lewiston Bridge (405) | 800 feet | |
| Continue onto General Brock Parkway (405) | 5.8 mi | |
| Merge left onto Queen Elizabeth Way (QEW N) | 30.8 mi | |
| Take the ramp towards 20 | 0.4 mi | |
| Keep right towards Red Hill Valley Parkway | 0.8 mi | |
| Continue onto Red Hill Valley Parkway | 5.2 mi | |
| Continue onto Lincoln M. Alexander Parkway | 6.3 mi | |
| Keep right towards 403 East: Highway 403 | 500 feet | |
| Keep left towards 403 West: Brantford | 0.7 mi | |
| Merge left onto Alexander Graham Bell Parkway (403 S) | 40.3 mi | |
| Merge left onto Highway 401 (401 W) | 31.0 mi | |
| Keep right onto Highway 402 Westbound (402 W) | 63.6 mi | |
| Continue onto Blue Water Bridge (402 W) | 1.2 mi | |
| Continue straight to stay on CBP - Port Huron Port Of Entry Traveler Lane | 600 feet | |
| Continue onto Blue Water Bridge Approach (I 69 W) | 2.7 mi | |
| Take exit 271 towards I 69: Flint | 66.1 mi | |
| Take exit 133 towards I 75: Detroit | 0.3 mi | |
| Keep right towards I 75 North: Saginaw | 0.3 mi | |
| Keep left towards I 75 North | 800 feet | |
| Merge left onto I 75 N | 277.8 mi | |
| Merge right onto I 75 S | 1.8 mi | |
| Continue onto Sault Ste. Marie International Bridge | 400 feet | |
| Make a slight right onto International Crossing | 900 feet | |
| Turn left onto Huron Street | 0.4 mi | |
| Turn left onto Wellington Street West | 800 feet | |
| Turn right onto Carmen's Way | 0.8 mi | |
| Turn right onto Second Line East (550) | 1.3 mi | |
| Turn left onto Great Northern Road (17) | 5.8 mi | |
| Continue onto Highway 17 (17) | 355.8 mi | |
| Turn left onto Railway Street | 300 feet | |
| You have arrived at your destination, on the right |
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Sudbury, Massachusetts - Nipigon, Ontario