US 412 $west, US 62; US 412 $west
216.2 mi4 hours 58 mins
| Head east on Church Street (TN 21) | 1.1 mi | |
| Turn right onto Carl Perkins Parkway (TN 78) | 0.6 mi | |
| Continue onto State Route 78 (TN 78) | 2.9 mi | |
| Continue onto 2nd Street (SR 78) | 800 feet | |
| Continue onto State Route 78 (TN 78) | 3.7 mi | |
| Continue onto Headden Drive (TN 78) | 1.0 mi | |
| Continue onto State Route 78 (TN 78) | 1.7 mi | |
| Turn right onto State Route 79 (TN 79) | 3.7 mi | |
| Continue onto SR 181 | 4.6 mi | |
| Continue onto Great River Road North (TN 181) | 4.9 mi | |
| Take the ramp on the right towards Saint Louis | 0.3 mi | |
| Merge left onto I 155 W | 15.7 mi | |
| Continue onto US 412 W | 13.0 mi | |
| Continue onto 1st Street (US 412) | 0.6 mi | |
| Turn left onto US 412 | 1.4 mi | |
| Enter the roundabout and take the 3rd exit onto US 412 | 300 feet | |
| Exit the roundabout onto US 412 | 62.3 mi | |
| Turn right onto US 63 | 33.4 mi | |
| Turn right | 400 feet | |
| Continue onto US 62 | 1.5 mi | |
| Turn left onto US 62 | 0.2 mi | |
| Keep right onto US 62 | 10.1 mi | |
| Turn right to stay on T & C Boulevard (US 62) | 49.8 mi | |
| Continue onto US 62B | 3.4 mi | |
| Turn right onto West 6th Street (Hwy 178) | 700 feet | |
| You have arrived at your destination |
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Tiptonville, Tennessee - Mountain Home, Arkansas