Crain Highway, James Madison Parkway
148.2 mi2 hours 40 mins
| Head north on Acton Lane | 0 feet | |
| Make a U-turn and continue on Acton Lane | 600 feet | |
| Turn right onto Crain Highway (US 301) | 22.5 mi | |
| Continue onto Nice Bridge (US 301) | 1.9 mi | |
| Continue onto James Madison Parkway (US 301) | 17.1 mi | |
| Continue onto James Madison Memorial Bridge (US 301) | 0.7 mi | |
| Continue onto A P Hill Boulevard (US 301) | 7.2 mi | |
| Continue onto Ambrose Powell Hill Junior Boulevard (US 301) | 4.1 mi | |
| Continue onto Bowling Green Bypass (US 301) | 2.5 mi | |
| Continue onto Rogers Clark Boulevard (VA 207) | 9.8 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto I 95 S | 18.8 mi | |
| Take the ramp on the left towards I 295 South: Rocky Mount NC | 1.8 mi | |
| Merge right onto I 295 | 13.1 mi | |
| Take the ramp towards I 64 East: Norfolk | 1.2 mi | |
| Merge left onto I 64 E | 32.3 mi | |
| Take the ramp towards VA 199: Lightfoot | 0.3 mi | |
| Turn right onto Humelsine Parkway (VA 199 E) | 8.0 mi | |
| Turn right onto Jamestown Road (VA 31) | 3.7 mi | |
| Turn left onto SR 359 | 0.3 mi | |
| Turn right onto Colonial National Historic Parkway | 1.1 mi | |
| Continue onto Island Drive | 0.4 mi | |
| Turn right to stay on Island Drive | 0.9 mi | |
| You have arrived at your destination |
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Waldorf, Maryland - Jamestown, Virginia