How to get from Washington, District of Columbia to Knoxville, Tennessee

Discover, print or download the driving directions for the best route to go from Washington, District of Columbia to Knoxville, Tennessee.

Enlarge the route map Washington, District of Columbia - Knoxville, Tennessee

Driving directions from Washington, District of Columbia to Knoxville, Tennessee

I 66 $west, I 81 $south

487.2 mi7 hours 23 mins

Head west on Constitution Avenue Northwest (US 1 N) 1.1 mi
Turn right onto 17th Street Northwest 0.3 mi
Turn left onto New York Avenue Northwest 700 feet
Continue onto E Street Northwest 900 feet
Go straight onto E Street Expressway 0.3 mi
Keep left towards I 66 West: Virginia 0.2 mi
Keep right towards I 66 West 500 feet
Merge left onto I 66 W 75.0 mi
Keep left towards I 81 South: Roanoke 0.6 mi
Merge right towards I 81 South: Roanoke 375.9 mi
Merge left onto I 40 31.5 mi
Take exit 388A towards SR 158 West: Downtown 0.3 mi
Keep left at the fork 0.9 mi
Continue onto James White Parkway (SR 158 W) 0.4 mi
Keep right onto Neyland Drive (SR 158 W) 800 feet
Take the ramp 0.3 mi
You have arrived at your destination

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Washington, District of Columbia - Knoxville, Tennessee

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