I 44 $east, I 55 $north
642.1 mi10 hours 16 mins
| Head east on MO 32 | 56.0 mi | |
| Turn right onto South Jefferson Avenue (MO 5) | 1.1 mi | |
| Take the ramp on the left towards I 44 East: Rolla | 0.3 mi | |
| Merge left onto I 44 E | 161.8 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep left towards I 55 North: Chicago | 0.6 mi | |
| Merge right onto I 55 N | 15.5 mi | |
| Keep left towards I 55 North: Chicago | 108.1 mi | |
| Keep right towards I 55 North: Chicago | 29.3 mi | |
| Keep left towards I 55 North: Chicago | 67.9 mi | |
| Continue onto I-55 N | 5.7 mi | |
| Continue onto I 55 N | 47.3 mi | |
| Take the ramp towards I 294 North: Wisconsin | 1.5 mi | |
| Keep left towards I 294 North: Wisconsin | 0.5 mi | |
| Merge left onto Tri-State Tollway (I 294 N) | 4.8 mi | |
| Keep left onto Tri-State Tollway (I 294 N) | 48.5 mi | |
| Continue onto I 41 | 59.5 mi | |
| Continue onto I 43 N | 4.3 mi | |
| Keep left towards WI 57 North: Plymouth | 24.4 mi | |
| Turn left onto Eastern Avenue (CTH C) | 1.6 mi | |
| Continue left onto East Mill Street (CTH C) | 0.4 mi | |
| You have arrived at your destination |
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West Madison, Missouri - Plymouth, Wisconsin