US 23 $south, I 77 $south
559.6 mi9 hours 18 mins
| Head west on Highland Road (M 59 W) | 11.7 mi | |
| Take the ramp on the left towards US 23 South: Ann Arbor | 0.4 mi | |
| Merge left onto US 23 S | 21.9 mi | |
| Keep left towards US 23 South: Plymouth | 0.5 mi | |
| Continue onto US 23 S | 1.9 mi | |
| Keep right towards US 23 South: Ann Arbor | 0.6 mi | |
| Continue onto US 23 S | 57.9 mi | |
| Continue onto I 475 S | 700 feet | |
| Take exit 1A towards I 75 South: Dayton | 0.6 mi | |
| Merge right onto I 75 S | 34.7 mi | |
| Take exit 156 towards US 68 | 2.5 mi | |
| Continue onto US 68 | 15.1 mi | |
| Continue onto US 23 | 7.2 mi | |
| Keep left onto US 23 | 56.2 mi | |
| Turn left onto East Powell Road (SR 750) | 0.7 mi | |
| Continue onto Polaris Parkway (SR 750) | 2.2 mi | |
| Take the ramp on the right | 0.5 mi | |
| Merge left onto I 71 S | 12.8 mi | |
| Take the ramp on the left towards I 70 East: Wheeling | 0.5 mi | |
| Merge right onto East Freeway (I 70) | 3.3 mi | |
| Take exit 105A towards US 33 East: Lancaster | 0.3 mi | |
| Merge left onto Southeast Expressway (US 33 E) | 9.1 mi | |
| Continue onto Columbus-Lancaster Road Northwest (US 33 E) | 7.6 mi | |
| Continue onto Lancaster Bypass (US 33 E) | 13.8 mi | |
| Continue onto Logan-Lancaster Road (US 33 E) | 3.5 mi | |
| Continue onto Logan-Lancaster Road Southeast (US 33 E) | 2.6 mi | |
| Continue onto Old Logan Road (US 33 E) | 31.6 mi | |
| Keep right towards US 33 East: Pomeroy | 0.2 mi | |
| Merge left onto James A. Rhodes Appalachian Highway (US 33 E) | 1.9 mi | |
| Keep right onto US 33 E | 19.0 mi | |
| Continue onto SR 833 | 1,000 feet | |
| Make a U-turn and continue on SR 124 | 1,000 feet | |
| Take the ramp onto SR 124 | 0.2 mi | |
| Turn right onto US 33 E | 18.6 mi | |
| Turn left onto US 33 | 2.7 mi | |
| Take the ramp onto US 33 E | 800 feet | |
| Merge left onto I 77 S | 145.2 mi | |
| Continue onto I 77 S | 26.0 mi | |
| Take the ramp towards SR 610: Wytheville | 0.4 mi | |
| Keep right at the fork | 500 feet | |
| Make a slight right onto Peppers Ferry Road (SR 610) | 0.9 mi | |
| Continue onto East Monroe Street | 400 feet | |
| Turn left onto North 11th Street | 300 feet | |
| Turn right onto North Main Street (US 11) | 1.3 mi | |
| Go straight onto Grayson Road (US 21) | 1.0 mi | |
| Continue onto Grayson Turnpike (US 21) | 15.2 mi | |
| Continue onto Elk Creek Parkway (US 21) | 11.3 mi | |
| Continue onto North Independence Avenue (US 21) | 1.9 mi | |
| Continue onto New River Parkway (US 21) | 3.7 mi | |
| Continue onto US Hwy 21 N (US 21) | 3.3 mi | |
| Turn left onto US Hwy 21 N (US 21) | 1.8 mi | |
| Continue onto North Main Street (US 21) | 0.4 mi | |
| Turn right onto North Sparta Parkway | 0.8 mi | |
| Turn right onto West Whitehead Street (NC 18) | 0.3 mi | |
| Continue onto NC Hwy 18 S (NC 18) | 2.9 mi | |
| You have arrived at your destination |
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White Lake, Michigan - Whitehead, North Carolina