Susquehanna Trail, I 81 $south
133.6 mi2 hours 29 mins
| Head northeast on West 3rd Street | 100 feet | |
| Turn right onto Market Street | 1.1 mi | |
| Make a slight left onto Montgomery Pike (US 15 S) | 20.4 mi | |
| Keep left onto Westbranch Highway (US 15 S) | 1.4 mi | |
| Continue onto North Derr Drive (US 15 S) | 1.5 mi | |
| Continue onto Westbranch Highway (US 15 S) | 11.6 mi | |
| Take the ramp towards US 11 South: Harrisburg | 33.0 mi | |
| Take the ramp towards US 22 East: Harrisburg | 0.3 mi | |
| Merge left onto Benvenue Road (US 22 E) | 11.2 mi | |
| Take the ramp towards PA 39: Linglestown | 0.2 mi | |
| Make a slight right | 100 feet | |
| Go straight onto Linglestown Road (PA 39 W) | 0.4 mi | |
| Turn left onto North Front Street | 0.7 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto George N Wade Bridge (I 81 S) | 0.8 mi | |
| Continue onto American Legion Memorial Highway (I 81 S) | 49.0 mi | |
| Take the ramp towards Lincoln Way | 0.3 mi | |
| Turn right onto Lincoln Way East (US 30) | 1.5 mi | |
| You have arrived at your destination |
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Williamsport, Pennsylvania - Chambersburg, Pennsylvania